Ian Willis, Ph.D., is a Professor at the Albert Einstein College of Medicine in the Departments of Biochemistry and Systems and Computational Biology. The Willis laboratory studies transcription by RNA polymerase (Pol) III in yeast and mouse models using molecular genetics, genomics and biochemical approaches. Our goal is to understand the function and regulation of the Pol III system in normal and disease states. The lab’s work over the last five years has focused on Pol III-related leukodystrophy and has led to the development of a mouse model of the disease.