2020 ULF Presentation with Dr. Geneviève Bernard
In this conference presentation, Dr. Geneviève Bernard, a prominent 4H Leukodystrophy researcher, updates our current understanding of 4H. After a brief genetics refresher, she explains myelin’s function and its relevance in 4H Leukodystrophy. Dr. Bernard also goes into detail about this disease at the molecular level: the role of POLR3 in the body, how genetic changes can disrupt it, and how specific genetic changes correlate to the outward presentation of 4H. It is complex information, but you can pause, rewind, and reference the glossary as needed.